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'A new era': Nuclear medicine being called new frontier in cancer care

'A new era': Nuclear medicine being called new frontier in cancer care
Often silent, too often deadly, ovarian cancer is historically hard to treat because we catch it late stage, um, 75% of the time it's stage 3 or stage 4, so we continue to struggle. For decades, standard of care was surgery and chemotherapy. Now NCH is offering *** cutting edge option called HIPEC. It works off those two treatments, delivering *** powerful punch. It is *** procedure that's done during surgery. Where the abdominal cavity is instilled with heated solution that has chemotherapy. HIPEC stands for hypothermic intraperitoneal chemotherapy. Heated chemo is flushed through the abdominal cavity to kill tiny cancer cells left behind after surgery. The heat actually makes the chemotherapy more effective, and it kills more cells than it would in normal temperature. Hot chemo is circulated through the abdomen. Then remove because it doesn't go through the bloodstream like IV chemo, it has fewer side effects. The dose that the cancer sees is much higher because there's direct exposure to the cancer cells. It's not given IV. It's in the abdominal cavity, you know, so your kidneys and your liver, etc. are going to see *** lower concentration of it, making this hot solution one more option for patients with advanced stage cancer. I'm Amy Osher reporting. Um,
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Updated: 12:32 PM EDT Apr 28, 2026
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'A new era': Nuclear medicine being called new frontier in cancer care
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Updated: 12:32 PM EDT Apr 28, 2026
Editorial Standards
Nuclear medicine is being called a new frontier in cancer care, and new research shows potential new uses for it in treating gastric and pancreatic cancers.Nuclear medicine that uses radioactive material is becoming much more popular, and doctors say it can be a lifesaver.Lori Canzanese is used to getting shots of radioactive material at Penn Medicine.Above video: Heated chemotherapy offers new hope for ovarian cancer patients"When you hear nuclear medicine or radioactive, it can feel pretty ominous," Canzanese said, "but the actual treatment was pretty calm."The 54-year-old mother of two was diagnosed with advanced neuroendocrine pancreatic cancer 10 years ago."It was overwhelming when I got that diagnosis," Canzanese said.After surgery, Penn's Department of Nuclear Medicine took over Canzanese's care. First, with advanced imaging to pinpoint the tumors, and then radioactive material to destroy cancer cells."After each treatment, I was considered hot with radiation," Canzanese said, "and so I had to be in isolation for three days."Dr. Phil Mulugeta said Canzanese's tumors were significantly reduced."Nuclear medicine is in a new era," Mulugeta said. "We can individually pick what kind of radioactive medication is the best for each individual patient."Mulugeta says several important research advances are expanding the horizons of nuclear medicine." is a scary word, but there's no need to be afraid," Mulugeta said. "These are special kinds of radioactive molecules. No patient has ever been harmed."Canzanese says the routine scans at Penn show her tumors are stable, giving her quality time with her family. She's working to help others with the annual Run for the Stripes, an event at the zoo that raises money and awareness for neuroendocrine tumors."I feel fortunate that this treatment was available," Canzanese said.Doctors say nuclear medicine can also be helpful in treating prostate and thyroid cancer.

Nuclear medicine is being called a new frontier in cancer care, and new research shows potential new uses for it in treating gastric and pancreatic cancers.

Nuclear medicine that uses radioactive material is becoming much more popular, and doctors say it can be a lifesaver.

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Lori Canzanese is used to getting shots of radioactive material at Penn Medicine.

Above video: Heated chemotherapy offers new hope for ovarian cancer patients

"When you hear nuclear medicine or radioactive, it can feel pretty ominous," Canzanese said, "but the actual treatment was pretty calm."

The 54-year-old mother of two was diagnosed with advanced neuroendocrine pancreatic cancer 10 years ago.

"It was overwhelming when I got that diagnosis," Canzanese said.

After surgery, Penn's Department of Nuclear Medicine took over Canzanese's care. First, with advanced imaging to pinpoint the tumors, and then radioactive material to destroy cancer cells.

"After each treatment, I was considered hot with radiation," Canzanese said, "and so I had to be in isolation for three days."

Dr. Phil Mulugeta said Canzanese's tumors were significantly reduced.

"Nuclear medicine is in a new era," Mulugeta said. "We can individually pick what kind of radioactive medication is the best for each individual patient."

Mulugeta says several important research advances are expanding the horizons of nuclear medicine.

"[Nuclear] is a scary word, but there's no need to be afraid," Mulugeta said. "These are special kinds of radioactive molecules. No patient has ever been harmed."

Canzanese says the routine scans at Penn show her tumors are stable, giving her quality time with her family.

She's working to help others with the annual Run for the Stripes, an event at the zoo that raises money and awareness for neuroendocrine tumors.

"I feel fortunate that this treatment was available," Canzanese said.

Doctors say nuclear medicine can also be helpful in treating prostate and thyroid cancer.

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